By Giancarlo Aldini,Kyung-Jin Yeum,Etsuo Niki,Robert M. Russell
Discovering delicate and particular biomarkers for systemic oxidative harm is key to appreciate the position of oxidative tension in human ailment. as soon as those roles are sincerely understood, we will establish novel drug and nutraceutical objectives. This quantity is going past traditional analytical tools of measuring total antioxidant task and offers perception to the invention of biomarkers that display info on particular components of oxidative rigidity. Contributed via a global record of specialists, Biomarkers for Antioxidant safeguard and Oxidative harm: rules and useful Applications describes either traditional biomarkers and up to date advancements during this area.
- Discusses traditional biomarkers in addition to fresh advances for measuring antioxidants and oxidative stress
- Biomarkers for lipid peroxidation: isoprostane, hydroxyloctadecaenoic acid, oxysterols, and reactive carbonyl species from lipid peroxidation
- Biomarkers for protein oxidation: carbonylation, tyrosine oxidation, ubiquitin-conjugation
- Biomarkers for DNA oxidative harm: comet assay, hydroxylated nucleotides, and exocylcic DNA adducts
- Recently constructed biomarkers from state-of-the-art technology
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