Nuclear Medicine in Pharmaceutical Research (TAYLOR & by M. FRIER,A C Perkins

By M. FRIER,A C Perkins

Radioactive tracers are taking part in an more and more vital function within the research of drug formula and drug supply structures, starting from the invention of latest medicines to the "in vivo" review of drug supply in people. this article defines the position and scope of nuclear drugs imaging suggestions (gamma scintigraphy) in pharmaceutical examine, giving info from medical trial facts. because the editors country, no different process can localise so exactly the web site of disintegration of a capsule within the gastro intestinal tract, the penetration of an aerosol within the lung or the place of abode time of a drug at the cornea. There are 10 chapters overlaying all facets of scintigraphic imaging utilized to pharmaceutical study, starting from the regulatory requisites, moral submission and examine approval in common human topics and sufferers teams, via to precise descriptions of particular functions. The introductory chapters offer descriptions of the fundamental instrumentation, thoughts, the rules of GMP utilized to radio labelling approaches and the significance of validation of goods and procedures.

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